Unleash the T-Cells….
Looks like the guys in the white lab coats up at U. of Penn’s Abramson Cancer Center and Perelman School of Medicine have created what they’re calling “Serial Killer” T cells. These are geneticallly engineered versions of patients’ own T-cells who are suffering from advanced CLL, a very bad leukemia.
This pilot trial of three patients with very few other options for treatment, showed that by removing the patients own T-Cells and modifying them and then putting them back into the patient’s body with new marching orders (so to speak) to seek and destroy the cancer cells.
And destroy they did….Dr. Carl June, a senior author in this study, said, “We saw at least a 1000-fold increase in the number of modified T cells in each of the patients. “…the infused T cells are serial killers. On average, each infused T cell led to the killing of thousands of tumor cells-and overall, destroyed at leasat two pounds of tumor in each patient.”
Patients had sustained remissions of up to a year in the study.
This breakthrough is 20 years in the making!! TWENTY YEARS!!!
I guess that gives you an idea of what it takes to break the back of cancer. This is a big result. A giant step from the lab to the killing machine that is cancer.
No doubt the method will be tested on other cancers too. We can only hope for the same results.
Super-charged T cells blowing up cancerous tumors…it’s a very pretty picture.
August 16, 2011 @ 5:12 am
Why do I bother calling up peolpe when I can just read this!
August 10, 2011 @ 6:45 pm
Good news for CLL…hope that the results can be replicated over and over again to produce sustained remissions.
This technique has been used in the treatment of advanced melanoma. I think that it produced some good initial results but it is not mentioned very much anymore at a melanoma board I visit. If it were producing sustainable results that were replicated in numerous patients, it would be talked about a great deal. If it failed in melanoma, it doesn’t mean that it will not work in CLL. It just means that these initial CLL patients in this trial must hope that it will work so that they and others might have another option. Sounds very promising especially to these 3 patients and their families. Hope is alive and well.
August 10, 2011 @ 5:59 pm
If only they can work the magic on some other cancers…what a wonderful world it would be.